COFFI (the international Collaborative on Fatigue Following Infection) was established following a meeting at the Royal Society of Medicine in London on the 4th and 5th of June 2015. The meeting was attended by leading researchers from post-infection cohort studies in the UK, Netherlands, Norway, USA, and Australia. These researchers share the common goal of trying to understand why infectious illnesses, such as glandular fever, cause long-term debilitating symptoms, particularly fatigue, in some people. If we can understand why an acute infection sometimes triggers chronic symptoms of sickness, we may gain insights into medically-unexplained diseases such as chronic fatigue syndrome (CFS, also known as ME or SEID), fibromyalgia, and irritable bowel syndrome (IBS).

COFFI is a collaborative group looking to work together to share resources, data and samples from multiple post-infection cohorts. Research undertaken on larger groups of patients will give researchers more statistical power to investigate aetiological (causal) mechanisms including possible clinical, genetic and environmental risk factors for post-infection fatigue and related syndromes.

The COFFI Group is open to any researcher working on post-infectious disease processes and welcomes new applicants for the project’s working group.